HA4682 Medical Grade Sodium Hyaluronate

Catalog No. HA4682
Appearance White powder
Protein ≤0.1%

Stanford Advanced Materials (SAM) offers medical grade hyaluronic acid powder for skin care applications; high molecular weight, middle/mild molecular weight, and low molecular weight sodium hyaluronate powder are available. CAS Number: 9067-32-7, the sample is available.

 

Medical Grade Hyaluronic Acid Description

Item No. Molecular Weight
HA-EPM1 0.2-4.0 m3/kg; 10K-3,000K Da
COA HA-EPM1
HA-EM2.0 (DMF) 1.3-1.5 m3/kg; 800K-1,300K Da
PDFCOA HA-EM2.0
HA-EM3.0 (DMF) 2.7-3.6 m3/kg; 1,600K-2,500K Da
PDFCOA HA-EM3.0
HA-PM-0.5 (DMF) 0.5-1.0 m3/kg; 20K-60K Da
PDFCOA HA-PM-0.5

Medical Grade Hyaluronic Acid Applications

For parenteral preparations or oral preparations not including intra-articular and intra-ocular preparations. It can be used in eye drops, contact lens solutions, topical preparations for wound or burn healing, medical lubricants, etc.

Medical Devices:

• ophthalmic surgery (viscosupplementation)                       • eye drops for dry eye (eg. artificial tears)

• intra-articular injections                                      • topical preparations for wound and burns healing

• intradermal injections for aesthetic correction                 • anti-adhesive and shape keeping products for thoracic and abdominal surgery

• anti-adhesive wound healing products                            • bandages with exudates absorbing capacity2.

Remedies /Drugs

Sodium hyaluronate on its own an active substance

• cartilage (joint) and tendon disorders                   • wound and burns healing preparations

Sodium hyaluronate in combination with other active substances

• anti-cancer preparations                                  • wound and burns healing preparations

• preparations for reduction of scar formation              • eye drops

• topical anti-inflammatory and analgesics preparations      • cartilage (joint) and tendon disorders

• nutraceuticals supporting the treatment  of skeleton or prevention of skeleton disorders                  • preparations for liver regeneration

Issue Engineering

• artificial skin grafts for plastic and reconstruction surgery                                                • artificial skin for the test of cosmetic raw material

• replacement of injured cartilage, artificial cartilage grafts                                                • artificial bone grafts

• adipose tissue replacement                                                                                   • support for the growth of soft tissue grafts

• aorta and large venous grafts industry

Biotechnology and Molecular Biology

• component of special cell culture medium                                                                     • supporting material for gene transfer

• biotinylated for detection of hyaluronan-binding proteins

Other Biological Applications

• sperm separation according to their mobility

• medium for in vitro ovum fertilization. For parenteral preparations or oral preparations not including intra-articular and intra-ocular preparations. It can be used in eye drops, contact lens solutions, topical preparations for wound or burn healing, medical lubricants, etc.

Items Specifications
Appearance White powder
Infrared absorption spectrophotometry Ph. Eur. Reference Standards
Appearance of solution A600nm≤0.01
pH (5mg/mL solution) 5.0-8.0
Intrinsic viscosity Measured values
Molecular weight Measured values
Sulfated glycosaminoglycans ≤1%
Nucleic acid A260nm≤0.5
Protein ≤0.1%
Chlorides ≤0.5%
Iron ≤80ppm
Heavy metals ≤20ppm
Loss on drying ≤20.0%
Bacterial counts ≤100cfu/g
Mold and Yeast ≤100cfu/g
Sodium hyaluronate 95%-105%
Glucuronic acid ≥42.0%

Medical Grade Hyaluronic Acid Functions

Viscoelasticity, protecting corneal endothelium;

Lubricating, viscoelasticity, repairing damage cartilage, inhibition of inflammation, pain relief, etc.;

Properties of good biocompatibility and degradability of HA and its derivatives.

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