Vitamin B3 Nicotinamide Description
Nicotinamide is a water-soluble form of vitamin B3 or niacin. It is made in the body by eating niacin-rich foods such as fish, poultry, nuts, legumes, eggs, and cereal grains. Nicotinamide supplements are used to treat skin conditions and niacin deficiencies.
Solubility:1g of the product dissolves in 2 ml of water, 1.5 ml of ethanol, and about 10 ml of glycerol. Soluble in acetone, amyl alcohol, chloroform, propylene glycol, and butanol. Practically insoluble in ether and benzene.
Vitamin B3 Nicotinamide Properties
| ITEM |
STANDARD |
| Assay.% |
98.5-101.5 (Hplc) |
| Identification a |
Conform (Ir) |
| Identification b (Ratio:a245/a262) |
0.63-0.67 (Uv) |
| Melting Range ℃ |
128-131 |
| Loss On Drying % |
=< 0.5 (Silica Gel Drier) |
| Residue On Ignition % |
=< 0.1( High Temperature Ignition) |
| Heavy Metals % |
=<0.003 (Colorimetry) |
| Readily Carbonizable Substances |
Conform (Colorimetry) |
Vitamin B3 Nicotinamide Function
Nicotinamide is an important part of the coenzyme Ⅰ and coenzyme Ⅱ in human and animal bodies, involved in lipid metabolism, tissue respiration, and carbohydrate oxidation during the process of anaerobic decomposition. It’s mainly used for medicine, food, and feed additives fields.
In animal feed additives, its main functions are： To prevent skin lesions and digestive diseases; promote animal growth, improve egg production and hatching rate, ensure good feather growth; treat mucosal inflammation and ulceration; prevent livestock and poultry persons.
In medicine and food additives, its main functions are： to prevent skin lesions and digestive diseases; to promote participation in the body of material and energy metabolism, to promote human growth and development; to treat a variety of mucosal inflammation and ulcers with other drugs; strong vasodilator effect, to improve the blood supply to the body function, feature a favorable effect on cerebral thrombosis, coronary heart disease, hyperlipidemia and so on; to treat nicotinic acid, nicotinamide deficiency caused by its long-term medicament of isonicotinic acid hydrazine and analogs.
Vitamin B3 Nicotinamide Applications
- Raw materials of drugs
- Skincare products
Reference:
- “Niacinamide Use During Pregnancy”. Drugs.com. Archived from the original on 30 December 2016. Retrieved 29 December 2016.
- Bender DA (2003). Nutritional Biochemistry of the Vitamins. Cambridge University Press. p. 203. ISBN 978-1-139-43773-8. Archived from the original on 30 December 2016.
- Williams AC, Cartwright LS, Ramsden DB (March 2005). “Parkinson’s disease: the first common neurological disease due to auto-intoxication?”. QJM. 98 (3): 215–26. doi:10.1093/qjmed/hci027
