HA4794 Vinpocetine, CAS 42971-09-5

Vinpocetine Description

Vinpocetine is a semi-synthetic alkaloid commonly used as an inhibitor of phosphodiesterase 1 (PDE1), blocking the hydrolysis of both cAMP and cGMP. In addition to its use as a selective PDE1 inhibitor in basic research, vinpocetine has diverse cerebral and neurological effects in vivo. Vinpocetine also directly inhibits the kinase activity of IKKβ and blocks TNF-α- and LPS-mediated activation of NF-κB in cells and in vivo. Stanford Advanced Materials (SAM) provides customers with high-quality vinpocetine at a very competitive price.

Vinpocetine is a partially synthesized supplement created from vincamine, which is derived from the seeds of the periwinkle plant.

Vinpocetine Specifications

Vinpocetine Applications

Vinpocetine can be used in the following fields:

• Laboratory research
• Treatment of cerebrovascular

FAQs about Vinpocetine 

Q: What is vinpocetine used for?

A: Vinpocetine is used to improve brain function, memory, and circulation, often for conditions like age-related cognitive decline, stroke recovery, or dementia.

Reference:

1. Jeon, K.I., Xu, X., Aizawa, T., et al. Vinpocetine inhibits NF-κB-dependent inflammation via an IKK-dependent but PDE-independent mechanism. Proceedings of the National Academy of Sciences of the United States of America 107(21), 9795-9800 (2016)
2. Medina, A.E. Therapeutic utility of phosphodiesterase type I inhibitors in neurological conditions. Front.Neurosci. 5(21), (2011).