Minoxidil Sulfate Specifications
Product Name |
Minoxidil Sulfate |
CAS Registry Number |
83701-22-8 |
Molecular Formula |
C9H15N5O4S |
Molecular Weight |
289.3 g/mol |
Purity |
≥95% |
Package |
1kg-25kg |
Storage |
Light Sensitive – Protect from Light |
Shelf life |
2 years |
Functions |
Accelerate animal and human hair growth, prevent hair loss, and lower blood pressure |
Minoxidil Sulfate Description
Minoxidil sulfate is a K+ channel agonist and a strong vascular smooth muscle relaxant. It has been shown to relax norepinephrine contraction and is reported to be a vasodilator. Minoxidil sulfate has been used to better understand the blood-brain tumor barrier in syngeneic and allogeneic rat studies and has been demonstrated to increase tumor permeability.
Minoxidil sulfate, a potent and ATP-sensitive K+ channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered a vasodilator to promote hair growth in vivo.
Minoxidil Sulfate Applications
- Pharmaceutical ingredients of topical medicine effective for hair loss treatment
Reference:
- Buhl, A., et al.: J. Invest. Dermatol., 95, 553 (1990)
- Meisheri, K.D., et al. 1988. J. Pharmacol. Exp. Ther. 245: 751-760.
- Winquist, R.J., et al. 1989. J. Pharmacol. Exp. Ther. 248: 149-156.
- Andersson, K.E., et al.: Pharmacol. Toxicol., 70, 244 (1992)
- Quast, U., et al. 1995. Naunyn Schmiedebergs Arch. Pharmacol. 353: 86-93.
- Black, K.L., et al. 2008. Brain Res. 1227: 198-206.