LU1139 Lutetium Fluoride (LuF3) Powder (CAS No. 13760-81-1)

SECTION 1. IDENTIFICATION

Product Name: Lutetium Fluoride

CAS #: 13760-81-1

Relevant identified uses of the substance: Scientific research and development

Supplier details:

Stanford Advanced Materials

E-mail: sales@samaterials.com

Tel: (949) 407-8904

Address: 23661 Birtcher Dr., Lake Forest, CA 92630 U.S.A.

SECTION 2. HAZARDS IDENTIFICATION

2.1 Classification of the substance or mixture

GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)

Acute toxicity, Oral (Category 3), H301

Acute toxicity, Inhalation (Category 3), H331

Acute toxicity, Dermal (Category 3), H311

2.2 GHS Label elements, including precautionary statements

Pictogram

Signal word Danger

Hazard statement(s)

H301 + H311 + H331 Toxic if swallowed, in contact with skin or if inhaled

Precautionary statement(s)

P261 Avoid breathing dust/ fume/ gas/ mist/ Vapors/ spray.

P264 Wash skin thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P271 Use only outdoors or in a well-ventilated area.P280 Wear protective gloves/ protective clothing.

P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor.

P302 + P352 IF ON SKIN: Wash with plenty of soap and water.

P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position

comfortable for breathing.

P312 Call a POISON CENTER/doctor if you feel unwell.

P322 Specific measures (see supplemental first aid instructions on this label).

P330 Rinse mouth.

P361 Remove/Take off immediately all contaminated clothing.

P363 Wash contaminated clothing before reuse.

P403 + P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

P501 Dispose of contents/ container to an approved waste disposal plant.

2.3 Hazards not otherwise classified (HNOC) or not covered by GHS

Contact with acids liberates very toxic gas.

Strong hydrogen fluoride-releaser

SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS

3.1 Substances

Formula : F3Lu

Molecular weight : 231.96 g/mol

CAS-No. : 13760-81-1

EC-No. : 237-355-8

Hazardous components

Component Classification Concentration

Lutetium trifluoride

Acute Tox. 3; H301 + H311 +

H331

<= 100 %

SECTION 4. FIRST AID MEASURES

4.1 Description of first aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous

area.Hydrofluoric

(HF) acid burns require immediate and specialized first aid and medical treatment. Symptoms may be

delayed up to 24

hours depending on the concentration of HF. After decontamination with water, further damage can

occur due to

penetration/absorption of the fluoride ion. Treatment should be directed toward binding the fluoride ion

as well as the

effects of exposure. Skin exposures can be treated with a 2.5% calcium gluconate gel repeated until

burning ceases.

More serious skin exposures may require subcutaneous calcium gluconate except for digital areas

unless the physician

is experienced in this technique, due to the potential for tissue injury from increased pressure.

Absorption can readily

occur through the subungual areas and should be considered when undergoing decontamination.

Prevention ofabsorption of the fluoride ion in cases of ingestion can be obtained by giving milk, chewable calcium

carbonate tablets

or Milk of Magnesia to conscious victims. Conditions such as hypocalcemia, hypomagnesemia and

cardiac arrhythmias

should be monitored for, since they can occur after exposure.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a

physician.

In case of skin contact

Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.First

treatment with

calcium gluconate paste.

In case of eye contact

Flush eyes with water as a precaution.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2)

and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5. FIREFIGHTING MEASURES

5.1 Extinguishing media

Suitable extinguishing media

Dry powder

5.2 Special hazards arising from the substance or mixture

No data available

5.3 Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

5.4 Further information

No data available

SECTION 6. ACCIDENTAL RELEASE MEASURES

6.1 Personal precautions, protective equipment and emergency procedures

Wear respiratory protection. Avoid dust formation. Avoid breathing Vapors, mist or gas. Ensure

adequate ventilation.

Evacuate personnel to safe areas. Avoid breathing dust.

For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal without creating dust. Sweep up and shovel. Do not flush with water.

Keep in suitable,

closed containers for disposal.

6.4 Reference to other sections

For disposal see section 13.

SECTION 7. HANDLING AND STORAGE

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols.

Provide appropriate exhaust ventilation at places where dust is formed.

For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Keep container tightly closed in a dry and well-ventilated place.

Never allow product to get in contact with water during storage. Do not store near acids.

Keep in a dry place. Do not store in glass

7.3 Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION

8.1 Control parameters

Components with workplace control parameters

Component CAS-No. Value Control

parameters

Basis

Lutetium trifluoride 13760-81-1 TWA 2.500000

mg/m3

USA. Occupational Exposure Limits

(OSHA) - Table Z-1 Limits for Air

Contaminants

Remarks CAS number varies with compound

TWA 2.500000

mg/m3

USA. Occupational Exposure Limits

(OSHA) - Table Z-2

Z37.28-1969

TWA 2.500000

mg/m3

USA. ACGIH Threshold Limit Values

(TLV)

Bone damage

Fluorosis

Substances for which there is a Biological Exposure Index or Indices

(see BEI® section)

Not classifiable as a human carcinogen

varies

TWA 2.500000

mg/m3

USA. ACGIH Threshold Limit Values

(TLV)

Bone damage

Fluorosis

Substances for which there is a Biological Exposure Index or Indices

(see BEI® section)

Not classifiable as a human carcinogen

variesTWA 2.5 mg/m3 USA. Occupational Exposure Limits

(OSHA) - Table Z-1 Limits for Air

Contaminants

CAS number varies with compound

TWA 2.5 mg/m3 USA. ACGIH Threshold Limit Values

(TLV)

Bone damage

Fluorosis

Substances for which there is a Biological Exposure Index or Indices

(see BEI® section)

Not classifiable as a human carcinogen

varies

Biological occupational exposure limits

Component CAS-No. Parameters Value Biological

specimen

Basis

Lutetium trifluoride 13760-81-1 Fluoride 3.0000

mg/g

In urine ACGIH - Biological

Exposure Indices

(BEI)

Remarks Prior to shift (16 hours after exposure ceases)

Fluoride 10.0000

mg/g

In urine ACGIH - Biological

Exposure Indices

(BEI)

End of shift (As soon as possible after exposure ceases)

Fluoride 2 mg/l Urine ACGIH - Biological

Exposure Indices

(BEI)

Prior to shift (16 hours after exposure ceases)

Fluoride 3 mg/l Urine ACGIH - Biological

Exposure Indices

(BEI)

End of shift (As soon as possible after exposure ceases)

8.2 Exposure controls

Appropriate engineering controls

Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling

the product.

Personal protective equipment

Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and approved under

appropriate

government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique

(without

touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves

after

use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

Material: Nitrile rubber

Minimum layer thickness: 0.11 mm

Break through time: 480 min

Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)Splash contact

Material: Nitrile rubber

Minimum layer thickness: 0.11 mm

Break through time: 480 min

Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)

data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test

method:

EN374

If used in solution, or mixed with other substances, and under conditions which differ from EN 374,

contact the

supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by

an

industrial hygienist and safety officer familiar with the specific situation of anticipated use by our

customers. It

should not be construed as offering an approval for any specific use scenario.

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected

according to

the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full-face particle

respirator type

N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the

respirator is the

sole means of protection, use a full-face supplied air respirator. Use respirators and components

tested and

approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES

9.1 Information on basic physical and chemical properties

a) Appearance Form: powder

Colour: white

b) Odor No data available

c) Odor Threshold No data available

d) pH No data available

e) Melting point/freezing

point

No data available

f) Initial boiling point and

boiling range

No data available

g) Flash point N/A

h) Evaporation rate No data available

i) Flammability (solid, gas) No data available

j) Upper/lower

flammability or

explosive limits

No data available

k) Vapor pressure No data available

l) Vapor density No data availablem) Relative density No data available

n) Water solubility No data available

o) Partition coefficient: noctanol/

water

No data available

p) Auto-ignition No data available

temperature

q) Decomposition

temperature

No data available

r) Viscosity No data available

s) Explosive properties No data available

t) Oxidizing properties No data available

9.2 Other safety information

No data available

SECTION 10. STABILITY AND REACTIVITY

10.1 Reactivity

No data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

No data available

10.4 Conditions to avoid

Avoid moisture.

Reacts dangerously with glass.

10.5 Incompatible materials

Strong reducing agentsglass

10.6 Hazardous decomposition products

Hazardous decomposition products formed under fire conditions. - Hydrogen fluoride, lutetium oxides

Other decomposition products - No data available

In the event of fire: see section 5

SECTION 11. TOXICOLOGICAL INFORMATION

11.1 Information on toxicological effects

Acute toxicity

No data available

No data available

Skin corrosion/irritation

No data available

Serious eye damage/eye irritation

No data available

Respiratory or skin sensitisation

No data available

Germ cell mutagenicity

No data available

Carcinogenicity

IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (Lutetium trifluoride)

NTP: No component of this product present at levels greater than or equal to 0.1% is identified as aknown or anticipated carcinogen by NTP.

OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a

carcinogen or potential carcinogen by OSHA.

Reproductive toxicity

No data available

No data available

Specific target organ toxicity - single exposure

No data available

Specific target organ toxicity - repeated exposure

No data available

Aspiration hazard

No data available

Additional Information

RTECS: OK8837500

Fluoride ion can reduce serum calcium levels possibly causing fatal hypocalcemia.

Salivation, Nausea, Abdominal pain, Vomiting, Fever, Rapid respiration, Fluoride ion can reduce

serum calcium levels

possibly causing fatal hypocalcemia., burning sensation, Cough, wheezing, laryngitis, Shortness of

breath, Headache

SECTION 12. ECOLOGICAL INFORMATION

12.1 Toxicity

No data available

12.2 Persistence and degradability

No data available

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Other adverse effects

No data available

SECTION 13. DISPOSAL CONSIDERATIONS

13.1 Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed

professional waste

disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent

and burn in a

chemical incinerator equipped with an afterburner and scrubber.

Contaminated packaging

Dispose of as unused product.

SECTION 14. TRANSPORT INFORMATION

DOT (US)UN number: 3288 Class: 6.1 Packing group: III

Proper shipping name: Toxic solid, inorganic, n.o.s. (Lutetium trifluoride)

Poison Inhalation Hazard: No

IMDG

UN number: 3288 Class: 6.1 Packing group: III EMS-No: F-A, S-A

Proper shipping name: TOXIC SOLID, INORGANIC, N.O.S. (Lutetium trifluoride)

IATA

UN number: 3288 Class: 6.1 Packing group: III

Proper shipping name: Toxic solid, inorganic, n.o.s. (Lutetium trifluoride)

SECTION 15. REGULATORY INFORMATION

SARA 302 Components

No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components

This material does not contain any chemical components with known CAS numbers that exceed the

threshold (De

Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards

Acute Health Hazard

Massachusetts Right To Know Components

No components are subject to the Massachusetts Right to Know Act.

Pennsylvania Right To Know Components

Lutetium trifluoride

CAS-No.

13760-81-1

Revision Date

2008-06-01

New Jersey Right To Know Components

Lutetium trifluoride

CAS-No.

13760-81-1

Revision Date

2008-06-01

California Prop. 65 Components

This product does not contain any chemicals known to State of California to cause cancer, birth

defects, or any other

reproductive harm.

SECTION 16. OTHER INFORMATION

Safety Data Sheet according to Regulation (EC) No. 1907/2006 (REACH). The above information is

believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The

information in this document is based on the present state of our knowledge and is applicable to the

product with regard to appropriate safety precautions. It does not represent any guarantee of the

properties of the product.