AS2645 Arsenic (III) Sulfide (As2S3) Powder (CAS 1303-33-9)

SECTION 1. IDENTIFICATION

Product Name: Arsenic(III) Sulfide

CAS #: 1303-33-9

Relevant identified uses of the substance: Scientific research and development

Supplier details:

Stanford Advanced Materials

E-mail: sales@samaterials.com

Tel: (949) 407-8904

Address: 23661 Birtcher Dr., Lake Forest, CA 92630 U.S.A.

SECTION 2. HAZARDS IDENTIFICATION

Classification of the substance or mixture in accordance with 29 CFR 1910 (OSHA HCS)

GHS06 Skull and crossbones

Acute Tox. 3 H301 Toxic if swallowed.

Acute Tox. 3 H331 Toxic if inhaled.

Hazards not otherwise classified

No data available

GHS label elements

GHS label elements, including precautionary statements

Hazard pictograms

GHS06

Signal word: Danger

Hazard statements

H301+H331 Toxic if swallowed or if inhaled.

Precautionary statements

P273 Avoid release to the environment.

P270 Do not eat, drink or smoke when using this product.P309 IF exposed or if you feel unwell:

P310 Immediately call a POISON CENTER/doctor/...

P302+P352 IF ON SKIN: Wash with plenty of water/...

P501 Dispose of contents/container in accordance with local/regional/national/international

regulations.

WHMIS classification

D1A - Very toxic material causing immediate and serious toxic effects

D2A - Very toxic material causing other toxic effects

Classification system

HMIS ratings (scale 0-4)

(Hazardous Materials Identification System)

Health (acute effects) = 3

Flammability = 0

Physical Hazard = 1

Other hazards

Results of PBT and vPvB assessment

PBT: N/A

vPvB: N/A

SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS

Substances

CAS No. / Substance Name:

1303-33-9 Arsenic(III) sulfide

Identification number(s):

EC number: 215-117-4

Index number: 033-002-00-5

SECTION 4. FIRST AID MEASURES

Description of first aid measures

General information

Immediately remove any clothing soiled by the product.

Remove breathing apparatus only after contaminated clothing has been completely removed.

In case of irregular breathing or respiratory arrest provide artificial respiration.

If inhaled:

Supply patient with fresh air. If not breathing, provide artificial respiration. Keep patient warm.

Seek immediate medical advice.

In case of skin contact:

Immediately wash with soap and water; rinse thoroughly.

Seek immediate medical advice.

In case of eye contact:

Rinse opened eye for several minutes under running water. Consult a physician.

If swallowed:

Do not induce vomiting; immediately call for medical help.

Information for doctor

Most important symptoms and effects, both acute and delayed

No data available

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5. FIREFIGHTING MEASURES

Extinguishing media

Suitable extinguishing agents

Product is not flammable. Use fire-fighting measures that suit the surrounding fire.

Special hazards arising from the substance or mixture

If this product is involved in a fire, the following can be released:

Arsenic oxides (AS2Ox)

Sulfur oxides (SOx)

Advice for firefighters

Protective equipment:

Wear self-contained respirator.

Wear fully protective impervious suit.

SECTION 6. ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Keep unprotected persons away.

Ensure adequate ventilation

Environmental precautions:

Do not allow material to be released to the environment without official permits.

Methods and materials for containment and cleanup:

Dispose of contaminated material as waste according to section 13.

Ensure adequate ventilation.

Prevention of secondary hazards:

No special measures required.

Reference to other sections

See Section 7 for information on safe handling

See Section 8 for information on personal protection equipment.

See Section 13 for disposal information.

SECTION 7. HANDLING AND STORAGE

Handling

Precautions for safe handling

Keep container tightly sealed.

Store in cool, dry place in tightly closed containers.

Ensure good ventilation at the workplace.

Open and handle container with care.

Information about protection against explosions and fires:

The product is not flammable

Conditions for safe storage, including any incompatibilities

Requirements to be met by storerooms and receptacles:

No special requirements.

Information about storage in one common storage facility:

Store away from oxidizing agents.

Further information about storage conditions:

Keep container tightly sealed.

Store in cool, dry conditions in well-sealed containers.

Specific end use(s)No data available

SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Additional information about design of technical systems:

Properly operating chemical fume hood designed for hazardous chemicals and having an average

face velocity of at least 100 feet per minute.

Control parameters

Components with limit values that require monitoring at the workplace:

Arsenic, elemental, and inorganic compounds (except arsine), as As

mg/m3

ACGIH TLV 0.01; Confirmed human carcinogen

Belgium TWA 0.2

Denmark TWA 0.05

Finland TWA Carcinogen

France VME 0.2

Hungary 0.5-STEL; Carcinogen

Korea TWA 0.01; Confirmed human carcinogen

Norway 0.02

Poland TWA 0.01

Sweden NGV 0.03; Carcinogen

Switzerland TWA 0.1; Carcinogen

United Kingdom TWA 0.1; Carcinogen

USA PEL 0.01

Additional information: No data

Exposure controls

Personal protective equipment

Follow typical protective and hygienic practices for handling chemicals.

Keep away from foodstuffs, beverages and feed.

Remove all soiled and contaminated clothing immediately.

Wash hands before breaks and at the end of work.

Store protective clothing separately.

Maintain an ergonomically appropriate working environment.

Breathing equipment:

Refer to 29CFR1910.1018 for regulations on respiratory protection required during exposure to

inorganic arsenic.

Use self-contained respiratory protective device in emergency situations.

Protection of hands:

Impervious gloves

Inspect gloves prior to use.

Suitability of gloves should be determined both by material and quality, the latter of which may vary by

manufacturer.

Eye protection: Safety glasses

Body protection: Protective work clothing.

SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties

Appearance:

Form: Solid in various forms

Odor: Like rotten eggsOdor threshold: No data available.

pH: N/A

Melting point/Melting range: 300 °C (572 °F)

Boiling point/Boiling range: 707 °C (1305 °F)

Sublimation temperature / start: No data available

Flash point: N/A

Flammability (solid, gas): No data available.

Ignition temperature: No data available

Decomposition temperature: No data available

Autoignition: No data available.

Danger of explosion:

Product does not present an explosion hazard.

Explosion limits:

Lower: No data available

Upper: No data available

Vapor pressure: N/A

Density at 20 °C (68 °F): 3.43 g/cm

3

(28.623 lbs/gal)

Relative density: No data available.

Vapor density: N/A

Evaporation rate: N/A

Solubility in Water (H

2

O): Insoluble

Partition coefficient (n-octanol/water): No data available.

Viscosity:

Dynamic: N/A

Kinematic: N/A

Other information

No data available

SECTION 10. STABILITY AND REACTIVITY

Reactivity

No data available

Chemical stability

Stable under recommended storage conditions.

Thermal decomposition / conditions to be avoided:

Decomposition will not occur if used and stored according to specifications.

Possibility of hazardous reactions

No dangerous reactions known

Conditions to avoid

No data available

Incompatible materials:

No data available

Hazardous decomposition products:

Arsenic oxides (As2Ox)

Toxic metal oxide fume

Sulfur oxides (SOx)

Hydrogen sulfide

SECTION 11. TOXICOLOGICAL INFORMATION

Information on toxicological effectsAcute toxicity:

Toxic if inhaled.

Toxic if swallowed.

LD/LC50 values that are relevant for classification:

Oral LD50 185 mg/kg (rat)

Dermal LD50 936 mg/kg (rat)

Skin irritation or corrosion:

May cause irritation

Eye irritation or corrosion:

May cause irritation

Sensitization:

No sensitizing effects known.

Germ cell mutagenicity:

No effects known.

Carcinogenicity:

EPA-A: human carcinogen: sufficient evidence from epidemiologic studies to support a causal

association between exposure and cancer.

IARC-1: Carcinogenic to humans: sufficient evidence of carcinogenicity.

ACGIH A1: Confirmed human carcinogen: Agent is carcinogenic to humans based on epidemiologic

studies of, or convincing clinical evidence in, exposed humans.

Carcinogen as defined by OSHA.

NTP-K: Known to be carcinogenic: sufficient evidence from human studies.

Reproductive toxicity: No effects known.

Specific target organ system toxicity - repeated exposure: No effects known.

Specific target organ system toxicity - single exposure: No effects known.

Aspiration hazard: No effects known.

Other information (about experimental toxicology):

Tumorigenic effects have been observed on tests with laboratory animals.

Subacute to chronic toxicity:

Acute arsenic poisoning from ingestion results in marked irritation of the stomach and intestines with

nausea, vomiting and diarrhea. In severe cases, the vomitus and stools are bloody and the patient

goes into collapse and shock with weak, rapid pulse, cold sweats, coma and death.

Chronic arsenic poisoning may cause disturbances of the digestive system such as loss of appetite,

cramps, nausea, constipation or diarrhea.

Subacute to chronic toxicity:

The Registry of Toxic Effects of Chemical Substances (RTECS) reports the following effects in

laboratory animals:

Behavioral - muscle weakness.

Lungs, Thorax, or Respiration - dyspnea.

Lungs, Thorax, or Respiration - tumors.

Gastrointestinal - hypermotility, diarrhea

Tumorigenic - equivocal tumorigenic agent by RTECS criteria.

Tumorigenic - tumors at site of application.

Additional toxicological information:

To the best of our knowledge the acute and chronic toxicity of this substance is not fully known

SECTION 12. ECOLOGICAL INFORMATION

Toxicity

Aquatic toxicity:

No data available

Persistence and degradability

No data availableBioaccumulative potential

No data available

Mobility in soil

No data available

Ecotoxical effects:

Remark:

Very toxic for aquatic organisms

Additional ecological information:

Do not allow material to be released to the environment without official permits.

Do not allow product to reach groundwater, water courses, or sewage systems, even in small

quantities.

Danger to drinking water if even extremely small quantities leak into the ground.

Also poisonous for fish and plankton in water bodies.

May cause long lasting harmful effects to aquatic life.

Avoid transfer into the environment.

Very toxic for aquatic organisms

Results of PBT and vPvB assessment

PBT: N/A

vPvB: N/A

Other adverse effects

No data available

SECTION 13. DISPOSAL CONSIDERATIONS

Waste treatment methods

Recommendation

Consult official regulations to ensure proper disposal.

Uncleaned packagings:

Recommendation:

Disposal must be made according to official regulations.

SECTION 14. TRANSPORT INFORMATION

UN-Number

DOT, IMDG, IATA

UN1557

UN proper shipping name

DOT

Arsenic compounds, solid, n.o.s.

IMDG, IATA

ARSENIC COMPOUND, SOLID, N.O.S.

Transport hazard class(es)

DOT

Class

6.1 Toxic substances.

Label

6.1

Class

6.1 (T5) Toxic substances

Label

6.1IMDG, IATA

Class

6.1 Toxic substances.

Label

6.1

Packing group

DOT, IMDG, IATA

III

Environmental hazards:

Environmentally hazardous substance, solid

Special precautions for user

Warning: Toxic substances

Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code

N/A

Transport/Additional information:

DOT

Marine Pollutant (DOT):

No

UN "Model Regulation":

UN1557, Arsenic compounds, solid, n.o.s., 6.1, III

SECTION 15. REGULATORY INFORMATION

Safety, health and environmental regulations/legislation specific for the substance or mixture

GHS GHS label elements, including precautionary statements

Hazard pictograms

GHS06

Signal word: Danger

Hazard statements

H301+H331 Toxic if swallowed or if inhaled.

Precautionary statements

P273 Avoid release to the environment.

P270 Do not eat, drink or smoke when using this product.

P309 IF exposed or if you feel unwell:

P310 Immediately call a POISON CENTER/doctor/...

P302+P352 IF ON SKIN: Wash with plenty of water/...

P501 Dispose of contents/container in accordance with local/regional/national/international

regulations.

National regulations

All components of this product are listed in the U.S. Environmental Protection Agency Toxic

Substances Control Act Chemical substance Inventory.

All components of this product are listed on the Canadian Domestic Substances List (DSL).

SARA Section 313 (specific toxic chemical listings)

1303-33-9 Arsenic(III) sulfide

California Proposition 65

Prop 65 - Chemicals known to cause cancer

1303-33-9 Arsenic(III) sulfide

Prop 65 - Developmental toxicity

Substance is not listed.

Prop 65 - Developmental toxicity, female

Substance is not listed.

Prop 65 - Developmental toxicity, male

Substance is not listed.Information about limitation of use:

For use only by technically qualified individuals.

This product contains arsenic and is subject to the reporting requirements of section 313 of the

Emergency Planning and Community Right to Know Act of 1986 and

40CFR372.

Other regulations, limitations and prohibitive regulations

Refer to 29CFR1910.1018 for regulations concerning inorganic arsenic.

Substance of Very High Concern (SVHC) according to the REACH Regulations (EC) No. 1907/2006.

Substance is not listed.

The conditions of restrictions according to Article 67 and Annex XVII of the Regulation (EC) No

1907/2006 (REACH) for the manufacturing, placing on the market and use must be observed.

Substance is not listed.

Annex XIV of the REACH Regulations (requiring Authorisation for use)

Substance is not listed.

Chemical safety assessment:

A Chemical Safety Assessment has not been carried out.

SECTION 16. OTHER INFORMATION

Safety Data Sheet according to Regulation (EC) No. 1907/2006 (REACH). The above information is

believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The

information in this document is based on the present state of our knowledge and is applicable to the

product with regard to appropriate safety precautions. It does not represent any guarantee of the

properties of the product.